Axis: Non-invasive brain stimulation for Alzheimer's disease.
Non-invasive brain stimulation for Alzheimer's disease.
Axis targets the memory and attention networks most affected by Alzheimer's. Helping strengthen the brain's natural connections without medication, without surgery.
Increase in left hippocampal activation after 12 weeks. Published rs-fMRI data (IntechOpen 2024, N=5).
Increase in temporal pole activation after 12 weeks. Fully traceable to peer-reviewed data.
No drugs. No surgery. Zero serious adverse events. Gentle stimulation delivered through the scalp.
What the research shows.
Our peer-reviewed rs-fMRI dataset demonstrated measurable changes in the brain regions most vulnerable to Alzheimer's pathology.
Default Mode Network (DMN)
The DMN is critical for memory retrieval, self-referential thinking, and autobiographical recall. It is one of the first networks to deteriorate in Alzheimer's. Our data shows a 580% increase in hippocampal activation after 12 weeks, reinforcing Axis's relevance to memory-associated circuitry.
Salience Network
The salience network governs attention, awareness, and the ability to switch between tasks. Impairment of this network contributes to the confusion and disorientation characteristic of Alzheimer's. Our data shows a 5,400% increase in temporal pole activation after 12 weeks.
If you're caring for someone with Alzheimer's, we understand the weight of that journey. This research represents early but meaningful evidence that non-invasive approaches can engage the very brain networks that matter most.
Targeting Alzheimer's at the network level.
Axis uses am-tPRNS with electrodes positioned over the supraorbital prefrontal cortex, targeting the forceps minor, a commissural fiber in the frontal lobe that connects both hemispheres. This engages the default mode network and salience network. The two systems most implicated in Alzheimer's pathology and most in need of support.
Sessions take 15 to 30 minutes. Over 12 to 16 weeks, repeated sessions promote long-term potentiation (LTP)-like plasticity in these memory and attention circuits, supporting cognitive function through the brain's own capacity to adapt.
Stay informed about Axis.
Axis is not yet commercially available. Join the waitlist to receive updates on research milestones and availability announcements.